Table 1.
The hub targets of RD in BC treatment and the topological parameters.
| Number | Gene name | Protein name | Degree |
|---|---|---|---|
| 1 | AKT1 | RAC-alpha serine/threonine-protein kinase | 94 |
| 2 | ESR1 | Estrogen receptor 1 | 88 |
| 3 | EGFR | Epidermal growth factor receptor | 87 |
| 4 | SRC | Proto-oncogene tyrosine-protein kinase Src | 82 |
| 5 | CASP3 | Caspase-3 | 80 |
| 6 | HSP90AA1 | Heat shock protein 90 alpha family class A member 1 | 79 |
| 7 | IGF1 | Insulin-like growth factor 1 | 59 |
| 8 | MDM2 | MDM2 proto-oncogene | 56 |
| 9 | RHOA | Ras homolog family member A | 55 |
| 10 | MAPK1 | Matrix metalloproteinase-1 | 55 |