Figure 3.

Fmr1 KO mice have higher LH and FSH. Serum levels of LH and FSH, (A) testosterone (T), progesterone (P) and inhibin B (Inh B) (B) in diestrus females in WT controls and Fmr1 KO. Each point represents one animal, while bars represent group means +/- standard error. LH was sampled from the tail tip after acclimatization to handling, to minimize stress and prevent exposure to isoflurane that may affect LH levels. FSH, T, P, Inh B samples are obtained from inferior vena cava. Statistical significance, indicated with a * (p < 0.05) was determined with t-test followed by Tukey’s post hoc test.