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Terpenoids from marine sponges. (A) Bioactive sponge-derived terpenoids: avarol from Dysidea avara, kalihinol A from Acanthella sp., and manoalide from Luffariella variabilis. (B) Reported isonitrile sesquiterpenes 1 to 5 from Bubarida sponges from San Diego. Boxed compounds are molecules validated from the uncharacterized Bubarida sample that was sequenced in this study and represent relative stereochemistry only (22). (C) in situ uncharacterized Bubarida sponge from San Diego.
