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Abnormal embryos are detected at 6.5 dpc. CGBP+/− animals were mated, and 6.5-dpc implantation sites were fixed, paraffin-embedded, and stained. (A) Normal 6.5-dpc embryo. The arrows indicate the presence of the embryonic ectoderm (ec) and endoderm (ee) as well as the ectoplacental cone (epc). (B) Abnormal (presumptively mutant) embryo. The lens objective was ×40.
