Table 3.
Cancer types in patients with Peutz-Jeghers syndrome
| Site | Male | Female | No. of cases | Median age at diagnosis, yr | Age range, yr |
|---|---|---|---|---|---|
| Gastrointestinal cancers | 12 | ||||
| Colorectal cancer | 2 | 1 | 3 | 59.2 | 56.9–66.6 |
| Small bowel cancer | 2 | 1 | 3 | 16.7 | 16.2–46.8 |
| Gastric cancer | 1 | 1 | 30.0 | 30.0 | |
| Pancreatic cancer | 2 | 2 | 4 | 51.0 | 43.6–67.6 |
| Cholangiocarcinoma | 1 | 1 | 63.4 | 63.4 | |
| Extra-gastrointestinal cancers | 16 | ||||
| Breast cancer | 6 | 6 | 39.7 | 23.0–45.2 | |
| Cervical cancer | 4 | 4 | 40.2 | 31.0–57.6 | |
| Thyroid cancer | 2 | 2 | 41.4 | 38.0–44.7 | |
| Testicular germ cell tumor | 1 | 1 | 52.6 | 52.6 | |
| Prostate cancer | 1 | 1 | 59.7 | 59.7 | |
| Oral cavity cancer | 1 | 1 | 34.3 | 34.3 | |
| Leukemia | 1 | 1 | 15.5 | 15.5 | |
| Total no. of cases | 11 | 17 | 28 | ||
| Total no. of patients | 9 | 12 | 21 |