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. 2023 Mar 7;6(3):e231860. doi: 10.1001/jamanetworkopen.2023.1860

Table 1. Descriptive Characteristics in the REGARDS Study Stratified by Baseline PSS Score.

Characteristic Participants, No. (%) P value
Total (N = 24 448) Low stress (PSS score <5) (n = 18 859) Elevated stress (PSS score ≥5) (n = 5589)
Age, median (range), y 64 (45-98) 64 (45-83) 62 (45-93) <.001
Sex
Male 9797 (40.1) 8101 (43.0) 1696 (30.3) <.001
Female 14 646 (59.9) 10 753 (57.0) 3893 (69.7)
Race
Black 10 177 (41.6) 7309 (38.8) 2868 (51.3) <.001
White 14 271 (58.4) 11 550 (61.2) 2721 (48.7)
Educational level
College graduate 8502 (34.8) 7145 (37.9) 1357 (24.3) <.001
Some college 6634 (27.1) 5170 (27.4) 1464 (26.2)
High school graduate 6393 (26.1) 4706 (25.0) 1687 (30.2)
<High school 2897 (11.8) 1820 (9.7) 1077 (19.3)
Annual income, $
<20 000 4323 (17.7) 2724 (14.4) 1599 (28.6) <.001
20 000-34 000 5765 (23.6) 4350 (23.1) 1415 (25.3)
35 000-74 000 7203 (29.5) 5895 (31.3) 1308 (23.4)
>75 000 3952 (16.2) 3469 (18.4) 483 (8.6)
Refused 3205 (13.1) 2421 (12.8) 784 (14.0)
Regiona
“Stroke belt” 8572 (35.1) 6501 (34.5) 2071 (37.1) <.001
“Stroke buckle” 5284 (21.6) 3993 (21.2) 1291 (23.1)
Nonbelt 10 592 (43.3) 8365 (44.4) 2227 (39.8)
CVD risk factors
Hypertension 14 364 (58.8) 10 793 (57.2) 3571 (63.9) <.001
Diabetes 5464 (22.3) 3918 (20.8) 1546 (27.7) <.001
Dyslipidemia 13 745 (56.2) 10 581 (56.1) 3164 (56.6) <.001
Health behaviors, No./total No. (%)
Physical activity
None 8526/24 091 (35.4) 6143/18 603 (33.0) 2383/5488 (43.4) <.001
1-3 times per week 8710/24 091 (36.2) 6873/18 603 (36.9) 1837/5488 (33.5)
≥4 times per week 6855/24 091 (28.5) 5587/18 603 (30.0) 1268/5488 (23.1)
BMI
Underweight 262/24 264 (1.1) 193/18 735 (1.0) 69/5529 (1.2) <.001
Normal 5789/24 264 (23.9) 4525/18 735 (24.2) 1264/5529 (22.9)
Overweight 8774/24 264 (36.2) 7040/18 735 (37.6) 1734/5529 (31.4)
Obese 9439/24 264 (38.9) 6977/18 735 (37.2) 2462/5529 (44.5)
Smoking
Current 3549/24 354 (14.6) 2410/18 792 (12.8) 1139/5562 (20.5) <.001
Past 9404/24 354 (38.6) 7487/18 792 (39.8) 1917/5562 (34.5)
Never 11 401/24 354 (46.8) 8895/18 792 (47.3) 2506/5562 (45.1)
Alcohol use
Heavy 948/23 993 (4.0) 723/16 802 (4.3) 173/5484 (3.2) <.001
Moderate 7954/23 993 (33.2) 5848/16 802 (34.8) 1538/5484 (28.0)
None 15 091/23 993 (62.9) 10 231/16 802 (60.9) 3773/5484 (68.8)

Abbreviations: BMI, body mass index; CVD, cardiovascular disease; PSS, Perceived Stress Scale; REGARDS, Reasons for Geographic and Racial Differences in Stroke.

a

The stroke belt and stroke buckle are the southeastern US states where rates of stroke are highest in the US. The stroke belt comprises North Carolina, South Carolina, Georgia, Tennessee, Mississippi, Alabama, Louisiana, and Arkansas. The stroke buckle comprises the coastal plains of North Carolina, South Carolina, and Georgia that have a higher stroke mortality rate than the remainder of the stroke belt.