Skip to main content
. Author manuscript; available in PMC: 2023 Mar 8.
Published in final edited form as: ACS Appl Mater Interfaces. 2022 Aug 8;14(33):37566–37576. doi: 10.1021/acsami.2c13019

Figure 9.

Figure 9.

(A) Image shows the histological analysis of heart collected from the mice after treating with 5 mg/kg DOX every other week for 3 weeks. H&E staining shows more nuclear staining, indicating a greater amount of toxicity than the healthy heart, and trichrome staining shows an accumulation of collagen in the toxic heart tissue when compared to healthy tissue. (B) Quantitative data of fibrosed area after analyzing the trichrome staining image by ImageJ. Injured heart treated with DOX had more fibrosis (21.86%) compared to that of healthy heart (2.35%). (C) ELISA of serum collected from the heart shows high level of troponin I in cardiotoxic mouse than healthy mouse.