Table 1.
Institution | Cohort and indications | Intraoperative management practice pattern |
Stanford University Medical Center Palo Alto, California [32] |
Nine CHLT recipients from 2006 to 2018. All patients with failing Fontan physiology and cirrhosis |
En bloc technique with patient maintained on CPB through simultaneous dual organ reperfusion. Two patients required intra-aortic balloon pump and one patient required VA ECMO to wean from CPB. |
Mayo Clinic Rochester, Minnesota [35] |
27 CHLT recipients from 1999 to 2013. Most common indication: hereditary amyloidosis |
VV bypass utilized for all patients undergoing LT via caval interposition technique. No form of bypass used for caval preserving technique. A small fraction remained on CPB during LT. |
The Hospital of the University of Pennsylvania Philadelphia, Pennsylvania [36] |
26 CHLT recipients from 1997 to 2013. Most common indications: heart failure from nonischemic, dilated, or congenital heart disease. |
All patients weaned from CPB without reversal of heparin and placed on VV bypass for LT. |
University of Chicago Medical Center Chicago, Illinois [38▪] |
Seven patients undergoing combined heart liver kidney transplant from 2018 to 2020. Most common indication: noncongenital heart disease. |
CPB transitioned to VA ECMO at completion of heart transplant to proceed with LT. |
Cedars-Sinai Medical Center Los Angeles, California [40] |
Six CHLT recipients from 1998 to 2014. Most common indication: hereditary amyloidosis. |
VV bypass with caval interposition technique used for all patients. |
Vanderbilt University Medical Center Nashville, Tennessee (Unpublished) |
17 CHLT recipients from 2017 to 2022. Most common indication: congenital heart disease. |
VA ECMO utilized in nearly half of recipients with congenital heart disease. |
CPB, cardiopulmonary bypass; CHLT, combined heart and liver transplantation; LT, liver transplantation; VA, venoarterial; VV, venovenous; ECMO, extracorporeal membrane oxygenation.