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. Author manuscript; available in PMC: 2023 Jul 10.
Published in final edited form as: Sci Signal. 2023 Jan 10;16(767):eabm5518. doi: 10.1126/scisignal.abm5518

Table 3. Gene set enrichment analysis of p38α and JNK1 hits.

FDR, false discovery rate.

JNK1 screen
 p38α screen
GO category FDR q-value GO category FDR q-value
Regulation of Intracellular Signal Transduction 1.44E-10 Chromatin Organization 9.80E-09
Nucleoside Triphosphatase Regulator Activity 5.82E-10 Chromosome Organization 2.73E-08
Cytoskeleton Organization 1.65E-09 Catalytic Complex 1.19E-07
Small GTPase Mediated Signal Transduction 2.85E-09 Positive Regulation of Biosynthetic Process 3.54E-07
Guanyl Nucleotide Exchange Factor Activity 7.90E-09 Positive Regulation of Nucleobase Containing Compound Metabolic Process 8.98E-07
Positive Regulation of Catalytic Activity 8.41E-09 Nuclear Protein Containing Complex 8.98E-07
Enzyme Regulator Activity 1.94E-08 Chromosome 2.65E-06
Positive Regulation of Molecular Function 1.94E-08 Positive Regulation of Transcription by RNA Pol II 3.04E-06
MAPK cascade 2.92E-08 Negative Regulation of Nucleobase Containing Compound Metabolic Process 1.04E-05
JNK cascade 5.55E-08 Covalent Chromatin Modification 1.28E-05