Extended Data Fig. 4. Per-generation mutation rates (similar to Fig. 1a) including published data on closely related species.

For each species, the colored squares represent the average per-generation observed rate, along with the 95% confidence intervals based on the binomial distribution, and the black points represent published estimates from similar or closely related species to those included in our dataset. For most of the species, these estimates lie within the 95% confidence intervals of our estimates. Published estimates are from: Felis catus (Wang et. al.²⁰), Mus musculus (Milholland et al.⁹³, Lindsay et al.³⁴), Pan troglodytes (Venn et al.²¹, Tatsumoto et al.²³, Besenbacher et al.¹⁶), Homo sapiens (Conrad et al.⁹⁴, Kong et al.⁶⁵, Francioli et al.³², Rahbari et al.⁹⁵, Wong et al.⁹⁶, Jónsson et al.²², Maretty et al.⁸², Turner et al.⁹⁷, Sasani et al.⁹⁸, Kessler et al.⁹⁹). The closely related species are from: close to the Salmo salar, Clupea harengus (Feng et al.⁵¹), close to Paralichthys olivaceus, the Cichlid (Malinsky et al.¹⁰⁰), close to Canis lupus familiaris, Canis lupus (Koch et al.¹⁰¹), close to Capra hircus, Bos taurus (Harland et al.¹⁰²), close to Mandrillus leucophaeus, Papio anubis (Wu et al.¹³), Macaca mulatta (Wang et al.¹⁴, Bergeron et al.¹²), and Chlorocebus sabaeus (Pfeifer¹⁰³), close to Saimiri boliviensis boliviensis, Aotus nancymaae (Thomas et al.¹⁷), close to Monodelphis domestica, Ornithorhynchus anatinus (Martin et al.⁴⁹), close to Taeniopygia guttata, Ficedula albicollis (Smeds et al.⁵⁰). See also Supplementary Table 8. The silhouette of Sygnathus was created by J.S. All other silhouettes are from PhyloPic (http://phylopic.org), except one of the silhouettes of S. harrissi, which was created by S. Werning, and the silhouette of P. troglodytes, which was created by T. M. Keesey (vectorization) and T. Hisgett (photography); both are available under a CC-BY 3.0 licence (https://creativecommons.org/licenses/by/3.0).