Table 1.
Demographic and clinical characteristics of patients and healthy controls per CMV status (population staining A and B).
| HC CMV- | HC CMV+ | MDD CMV- | MDD CMV+ | Test statistic | p-value | |
|---|---|---|---|---|---|---|
| n (%) | 73 (64.6) | 40 (35.4) | 75 (59.1) | 52 (40.9) | χ2 = 0.56 | 0.45 |
| female, n (%) | 46 (63.0) | 32 (80.0)a | 37 (49.3) | 42 (80.8)a | χ2 = 17.94 | <0.001 |
| age (years), Md (IQR) | 37 (20.88) | 40.32 (26.55) | 37 (19) | 44.2 (15.675) | χ2 = 5.63 | 0.13 |
| CMV titer (U/mL), Md (IQR) | 4 (1.9) | 58.9 (43.85) | 3.7 (2.02) | 59.59 (40.83) | χ2 = 170.08 | <0.001 |
| BMI, Md (IQR) | 23.55 (4.97) | 23.13 (4.39) | 24.54 (5.03) | 23.39 (4.34)a | χ2 = 9.62 | 0.02 |
| overweight/obese, n (%) | 21 (28.8) | 13 (32.5) | 35 (46.7) | 13 (25.0)a | χ2 = 251.95 | <0.001 |
| CTQ sum score, Md (IQR) | 31 (9) | 30 (11.25) | 33.5 (14.75) | 42 (23)a | χ2 = 22.37 | <0.001 |
| childhood trauma present, n (%) | 25 (34.2) | 11 (27.5) | 38 (50.7) | 31 (59.6) | χ2 = 13.75 | 0.003 |
| medicated (psychotrop.), n (%) | 0 (0.0) | 0 (0.0) | 53 (94.6) | 37 (92.5) | 0.69 |
Notes. MDD Major depressive disorder; HC healthy controls; CMV cytomegalovirus; Md median; IQR interquartile range. Chi-square test or Fisher's exact test were performed for contingency tables, as well as Kruskal-Wallis tests for continuous outcomes.
a
Indicating significant differences as described in the section 3.1 Demographics.