Table 3.
T cytotoxic cell subpopulations in MDD and HC as frequency of CD3+cells (staining C).
| HC CMV- | HC CMV+ | MDD CMV- | MDD CMV+ | Test statistic | p-value | |
|---|---|---|---|---|---|---|
| CD8 T naive, Md (IQR) | 14.7 (8.8) | 12.5 (6.8) | 15.6 (6.3) | 19 (9.3) | χ2 = 2.36 | 0.50 |
| CD8 T memory, Md (IQR) | 11.4 (6.2) | 14.2 (6.5) | 9.62 (6.8) | 18.2 (11.4)* | χ2 = 10.6 | 0.01 |
| CD8 Tcm, Md (IQR) | 0.62 (0.47) | 0.77 (0.72) | 0.65 (0.67) | 0.45 (0.75) | χ2 = 2.24 | 0.52 |
| CD8 Tem, Md (IQR) | 2.43 (2.35) | 2.22 (1.72) | 1.95 (2.34) | 1.8 (2.61) | χ2 = 0.45 | 0.93 |
| CD8 TEMRA, Md (IQR) | 7.9 (4.2) | 9.4 (5.25) | 6.85 (3.9) | 12 (7.45)* | χ2 = 15.66 | 0.001 |
Notes. As frequency of CD3+. *CD8 T memory cell frequencies of the MDD group with CMV were increased compared to their counterparts without CMV as a strong statistical trend (p = 0.05) and CD8 TEMRA cell frequencies of the MDD group with CMV were significantly higher than their counterparts without CMV (p = 0.01).