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. 2023 Feb 23;14:1141199. doi: 10.3389/fimmu.2023.1141199

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Copyright © 2023 Guo, Zhang, Dong, Yan, Wang, Cao, Rao, Fan, Yang, Huang and Zhou

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The prognostic efficiency of PIMET score in subgroups of patients receiving lenvatinib monotherapy or lenvatinib plus ICI for unresectable HCC. Median OS (Kaplan-Meier method) and hazard ratios (univariable Cox regression) for death comparing PIMET categories (0 vs. 1 and 0 vs. 2 points) in different subgroups in the whole cohort. AFP, alpha-fetoprotein; CI, confidence interval; ECOG, Eastern Cooperative Oncology Group performance status; HBV, hepatitis B virus; HCC, hepatocellular carcinoma; HR, hazard ratio; ICI, immune checkpoint inhibitor; mOS, median overall survival; MVI, macrovascular invasion.