Table 2.
Univariate and multivariate regression analysis of SAI.
| Variable | Univariate regression | Multivariate regression | ||
|---|---|---|---|---|
| OR (95% CI) | p-value | OR (95% CI) | p-value | |
| Age (years) | 1.054 (1.035–1.073) | <0.001 | 1.028 (1.007–1.049) | 0.008 |
| Male | 0.560 (0.414–0.760) | <0.001 | ||
| Smoking | 0.667 (0.476–0.935) | 0.019 | ||
| Drinking | 0.731 (0.498–1.074) | 0.111 | ||
| BMI (kg/m2) | 0.886 (0.851–0.922) | <0.001 | 0.911 (0.872–0.952) | <0.001 * |
| Sarcopenia risk | 2.252 (1.645–3.084) | <0.001 | 1.454 (1.008–2.097) | 0.045 |
| Stroke etiology | ||||
| Large-artery atherosclerosis | Reference | |||
| Cardioembolism | 1.567 (0.924–2.658) | 0.096 | ||
| Small vessel occlusion | 0.925 (0.619–1.384) | 0.706 | ||
| Other determined etiology | 0.797 (0.391–1.627) | 0.534 | ||
| Undetermined etiology | 1.100 (0.684–1.770) | 0.695 | ||
| NIHSS categories | ||||
| 0–4 | Reference | Reference | ||
| 5–15 | 3.663 (2.656–5.051) | <0.001 | 2.624 (1.842–3.738) | <0.001 * |
| >16 | 11.172 (4.491–27.794) | <0.001 | 5.801 (2.047–16.44) | 0.001 |
| Diabetes | 2.437 (1.793–3.312) | <0.001 | 1.962 (1.391–2.769) | <0.001 * |
| Hypertension | 1.162 (0.811–1.664) | 0.414 | ||
| Dyslipidemia | 1.809 (1.282–2.553) | 0.001 | ||
| Coronary artery disease | 0.861 (0.600–1.237) | 0.418 | ||
| Chronic heart failure | 2.319 (0.751–7.161) | 0.144 | ||
| Atrial fibrillation | 1.594 (0.956–2.660) | 0.074 | ||
| COPD | 1.964 (0.961–4.134) | 0.064 | ||
| HB (g/L) | 0.991 (0.982–1.000) | 0.058 | ||
| FBG (mmol/L) | 1.046 (1.010–1.082) | 0.010 | ||
| SCr (μmol/L) | 1.000 (0.998–1.002) | 0.804 | ||
| eGFR (ml/min*1.73 m2) | 0.992 (0.985–0.998) | 0.013 | ||
| Uric acid (μmol/L) | 1.000 (0.999–1.002) | 0.785 | ||
| Total bilirubin (μmol/L) | 1.019 (0.998–1.040) | 0.083 | ||
| Direct bilirubin (μmol/L) | 0.955 (0.897–1.016) | 0.147 | ||
| ALT (U/L) | 0.990 (0.979–1.001) | 0.070 | ||
| ALB (g/L) | 0.830 (0.799–0.863) | <0.001 | 0.866 (0.831–0.901) | <0.001 * |
| TC (mmol/L) | 0.971 (0.864–1.091) | 0.624 | ||
| TG (mmol/L) | 1.009 (0.909–1.121) | 0.861 | ||
| D-dimmer (μmol/L) | 0.999 (0.997–1.001) | 0.359 | ||
OR, odds ratio; CI, confidence interval; BMI, body mass index; NIHSS, National Institutes of Health Stroke Scale; COPD, chronic obstructive pulmonary disease; HB, hemoglobin; FBG, fast blood glucose; SCr, serum creatinine clearance; eGFR, estimated glomerular filtration rate; ALT, alanine aminotransferase; ALB, album; TC, total cholesterol; TG, triglyceride. Bold means a value of p of ≤ 0.05; Bold* means a p-value of ≤ 0.001.