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. 2023 Mar 8;14:999. doi: 10.1038/s41467-023-35908-3

Fig. 7. Illustration of the known cellular processes implicated in YARS1CMT.

Fig. 7

The enhanced F-actin bundling properties described for YARS1CMT in this study might contribute to global protein synthesis inhibition, activation of the integrated stress response, transcriptional disregulation, and impaired synaptic vesicle mobility.