Table 3.

Histopathological changes in testes of rats injected intraperitoneally with different concentrations of AgNPs for 30 days post-AgNP administration

Lesions after 30 days of exposure	(0.25 mg/kg b.w.)	(0.5 mg/kg b.w.)	(1.0 mg/kg b.w.)
Congestion	−	−	+
Interstitial edema	−	−	−
Vacuolar degeneration	+	+  +	+  +
Tubular degeneration/desquamation	+	+  +	+  +  +
Tubular irregularities	+	+  +	+  +  +
Tubular necrosis/atrophy	+  +	+  +  +	+  +  +  +
Retarded spermatogenesis	+	+  +	+  +  +
Brown pigment	−	−	+

 − , negative; + , mild; +  + , moderate; +  +  + / +  +  +  + , severe