Table 2.
One-Year Incidence of CDI/100,000 Person-Years from 2012–2017 in Persons with Commercial or Medicaid Health Insurance By Coding for Immunocompetent and Immunocompromising Conditions During their First Year of Enrollmenta
| Commercially Insured | Medicaid Insured | |||||||
|---|---|---|---|---|---|---|---|---|
| Conditions | PY | # of Episodes | Incidence (Episodes/100,000 PY) | PY | # of Episodes | Incidence (Episodes/100,000 PY) | IRR (Medicaid: Commercial) | P |
| Chronic Medical Conditions | ||||||||
| Any chronic medical condition | 2813966.0 | 4393 | 156.1 | 535050.6 | 2315 | 432.7 | 2.8 | <0.001 |
| Chronic lung disease | 723646.3 | 1562 | 215.9 | 239638.8 | 1099 | 458.6 | 2.1 | <0.001 |
| Diabetes | 1619289.6 | 2164 | 133.6 | 223661.9 | 1034 | 462.3 | 3.5 | <0.001 |
| Heart disease | 542857.3 | 1212 | 223.3 | 95301.6 | 615 | 645.3 | 2.9 | <0.001 |
| Alcohol abuse | 98399.1 | 373 | 379.1 | 87704.3 | 547 | 623.7 | 1.6 | <0.001 |
| Liver disease | 93867.8 | 475 | 506.0 | 32572.0 | 364 | 1117.5 | 2.2 | <0.001 |
| Cystic fibrosis | 47305.4 | 88 | 186.0 | 3752.4 | 20 | 533.0 | 2.9 | <0.001 |
| Immunocompromising conditions | ||||||||
| Any immunocompromising condition | 1313330.8 | 6619 | 504.0 | 166340.4 | 2262 | 1359.9 | 2.7 | <0.001 |
| AIDs | 48893.3 | 145 | 296.6 | 16338.4 | 187 | 1144.5 | 3.9 | <0.001 |
| Chronic kidney disease | 95622.1 | 918 | 960.0 | 24917.1 | 483 | 1938.4 | 2.0 | <0.001 |
| End stage renal disease | 28686.1 | 786 | 2740.0 | 6980.9 | 268 | 3839.1 | 1.4 | <0.001 |
| Nephrotic disease | 2397.9 | 15 | 625.5 | 353.1 | 8 | 2265.6 | 3.6 | 0.002 |
| Inflammatory bowel disease | 111345.6 | 1356 | 1217.8 | 10235.6 | 348 | 3399.9 | 2.8 | <0.001 |
| Rheumatoid arthritis/connective tissue disease | 492888.8 | 1291 | 261.9 | 51962.7 | 352 | 677.4 | 2.6 | <0.001 |
| Bone marrow/stem cell transplant | 5108.0 | 184 | 3602.2 | 644.6 | 35 | 5429.5 | 1.5 | 0.025 |
| Solid organ transplant | 28019.6 | 438 | 1563.2 | 1564.1 | 40 | 2557.4 | 1.6 | 0.003 |
| Immunodeficiency | 51754.8 | 1020 | 1970.8 | 17331.9 | 584 | 3369.5 | 1.7 | <0.001 |
| Leukemia | 19413.8 | 307 | 1581.3 | 2039.9 | 63 | 3088.4 | 2.0 | <0.001 |
| Lymphoma | 47858.5 | 539 | 1126.2 | 4721.4 | 92 | 1948.6 | 1.7 | <0.001 |
| Solid tumor | 469804.1 | 1791 | 381.2 | 49455.2 | 579 | 1170.8 | 3.1 | <0.001 |
| Metastatic cancer | 55728.0 | 693 | 1243.5 | 14074.1 | 247 | 1755.0 | 1.4 | <0.001 |
| Radiotherapy | 74112.7 | 572 | 771.8 | 17617.8 | 224 | 1271.4 | 1.6 | <0.001 |
| No Chronic Medical Conditions And No Immunocompromised Conditions | 32662276.6 | 14904 | 45.6 | 3006447.5 | 2033 | 67.6 | 1.5 | <0.001 |
a
The first year of enrollment in the Commercial or Medicaid Database, 2011–2017.
All comparisons of incidence rates between Commercially- and Medicaid-insured persons were significant with p < 0.001, except cystic fibrosis (p = 0.0253) and nephrotic syndrome (p = 0.0016).