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. Author manuscript; available in PMC: 2024 Jun 1.
Published in final edited form as: J Physiol. 2022 Sep 27;601(11):2139–2163. doi: 10.1113/JP283261

Figure 1. Dietary restriction of histidine, phenylalanine or threonine improves body composition.

Figure 1.

(A) Experimental scheme. (B-E) Change in body weight (B), fat mass (C), lean mass (D), and body composition (E) of mice consuming the indicated diets for the indicated time (n=8–9 mice per group, *p<0.05, Dunnett’s test vs. Ctrl AA following a mixed-effects model (Restricted Maximum Likelihood (REML)). (F-G) Food consumption per mouse (F) and normalized to body weight of mice (G) fed the indicated diets (n=8–9 per group, *p<0.05, Dunnet’s test vs. Ctrl AA conducted separately for the light and dark cycles post 2-way RM ANOVA). Data represented as mean ± SEM.