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. Author manuscript; available in PMC: 2024 Jun 1.
Published in final edited form as: J Physiol. 2022 Sep 27;601(11):2139–2163. doi: 10.1113/JP283261

Figure 5. Restricting dietary histidine improves the metabolic health of DIO mice.

Figure 5.

(A) Experimental scheme. (B-E) Body weight (B), fat mass (C), lean mass (D), and body composition (E) of mice consuming the indicated diets for the indicated time (n=10–12 mice per group, *p<0.05, Dunnett’s test vs. WD Ctrl AA post 2-way RM ANOVA). (F) Metabolic chambers were used to assess multiple components of energy balance including food consumption normalized to body weight (n=5–8 per group, *p<0.05, Dunnet’s test vs. WD Ctrl AA conducted separately for the light and dark cycles post 2-way RM ANOVA).