Table 1.
Diet composition of diets used to investigate the effect of reduced levels of essential amino acids in the context of a normal calorie diet.
| Amino Acid Diets | Ctrl AA | Low Thr | Low Phe | Low His | Low Met | Low Lys | Low Trp |
|---|---|---|---|---|---|---|---|
| Teklad Diet name | 21% Protein | Thr 2/3 Adj Diet | Phe and Tyr Adj Diet | His 2/3 Adj Diet | Met 2/3 Adj Diet | Lys 2/3 Adj Diet | Trp 2/3 Adj Diet |
| Teklad Diet number | TD.140711 | TD.160236 | TD.160235 | TD.160237 | TD.160073 | TD.160075 | TD.160074 |
| Color | Red | Orange | Green | Yellow | Green | Black | Orange |
| Formula | g/kg | g/kg | g/kg | g/kg | g/kg | g/kg | g/kg |
|
| |||||||
| L-Alanine | 9.38 | 9.9915 | 9.966 | 9.8739 | 9.7175 | 11.0559 | 9.6309 |
| L-Arginine | 6.3 | 6.3 | 6.3 | 6.3 | 6.3 | 6.3 | 6.3 |
| L-Asparagine | 20.58 | 21.0334 | 21.0146 | 20.9462 | 20.8302 | 21.8226 | 20.766 |
| L-Aspartic Acid | 20.58 | 21.4939 | 21.4557 | 21.318 | 21.0843 | 23.0843 | 20.9549 |
| L-Cysteine | 7.2 | 7.2 | 7.2 | 7.2 | 7.2 | 7.2 | 7.2 |
| L-Glutamic Acid | 28.97 | 29.9797 | 29.9377 | 29.7856 | 29.5272 | 31.7374 | 29.3843 |
| L-Glutamine | 33.77 | 34.2759 | 34.2549 | 34.1786 | 34.0492 | 35.1564 | 33.9775 |
| Glycine | 2.96 | 3.475 | 3.4537 | 3.376 | 3.2443 | 4.3718 | 3.1713 |
| L-Histidine HCl, monohydrate | 4.6 | 4.6 | 4.6 | 1.5 | 4.6 | 4.6 | 4.6 |
| L-Isoleucine | 7.8 | 7.8 | 7.8 | 7.8 | 7.8 | 7.8 | 7.8 |
| L-Leucine | 25.4 | 25.4 | 25.4 | 25.4 | 25.4 | 25.4 | 25.4 |
| L-Lysine HCl | 20.38 | 20.38 | 20.38 | 20.38 | 20.38 | 6.64 | 20.38 |
| L-Methionine | 6.7 | 6.7 | 6.7 | 6.7 | 2.18 | 6.7 | 6.7 |
| L-Phenylalanine | 6.6 | 6.6 | 2.15 | 6.6 | 6.6 | 6.6 | 6.6 |
| L-Proline | 7.41 | 8.199 | 8.167 | 8.0479 | 7.8459 | 9.5748 | 7.7341 |
| L-Serine | 7.41 | 8.1311 | 8.1012 | 7.9924 | 7.808 | 9.3864 | 7.7058 |
| L-Threonine | 9.7 | 3.16 | 9.7 | 9.7 | 9.7 | 9.7 | 9.7 |
| L-Tryptophan | 3.4 | 3.4 | 3.4 | 3.4 | 3.4 | 3.4 | 1.1 |
| L-Tyrosine | 6.9 | 6.9 | 2.25 | 6.9 | 6.9 | 6.9 | 6.9 |
| L-Valine | 8.4 | 8.4 | 8.4 | 8.4 | 8.4 | 8.4 | 8.4 |
|
| |||||||
| Sucrose | 291.248 | 291.248 | 291.248 | 291.248 | 291.248 | 291.248 | 291.248 |
| Corn Starch | 150.0 | 150.5 | 151.9 | 149.3 | 150.7 | 149.3 | 150.0 |
| Maltodextrin | 150.0 | 150.5 | 151.9 | 149.3 | 150.7 | 149.3 | 150.0 |
| Anhydrous Milkfat | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| Cholesterol | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| Corn Oil | 52.0 | 52.0 | 52.0 | 52.0 | 52.0 | 52.0 | 52.0 |
| Olive Oil | 29.0 | 29.0 | 29.0 | 29.0 | 29.0 | 29.0 | 29.0 |
| Cellulose | 30.0 | 30.0 | 30.0 | 30.0 | 30.0 | 30.0 | 30.0 |
| Mineral Mix, AIN-93M-MX (94049) | 35.0 | 35.0 | 35.0 | 35.0 | 35.0 | 35.0 | 35.0 |
| Calcium Phosphate Ca(H2PO4)2 · H2O | 8.2 | 8.2 | 8.2 | 8.2 | 8.2 | 8.2 | 8.2 |
| Vitamin Mix, Teklad (40060) | 10.0 | 10.0 | 10.0 | 10.0 | 10.0 | 10.0 | 10.0 |
| TBHQ, antioxidant | 0.012 | 0.012 | 0.012 | 0.012 | 0.012 | 0.012 | 0.012 |
| Food Coloring | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 |
|
| |||||||
| % kcal from | |||||||
|
| |||||||
| Protein (based on N x 6.25) | 22 | 22 | 22 | 24.1 | 23.8 | 24.2 | 23.9 |
| Carbohydrates | 59.4 | 59.4 | 58.3 | 57.8 | 58.2 | 57.6 | 57.9 |
| Fat | 18.6 | 18.6 | 18.2 | 18.2 | 18.2 | 18.1 | 18.2 |
| Kcal/g | 3.9 | 3.9 | 4 | 4 | 4 | 4 | 3.9 |