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. Author manuscript; available in PMC: 2023 May 7.
Published in final edited form as: Neuroimage. 2022 Sep 9;263:119621. doi: 10.1016/j.neuroimage.2022.119621

Table 3.

Multilevel modeling results for group type stable cognitively normal (sCN) compared to progressive mild cognitive impairment (pMCI). Bold p-values are <0.05.

Estimate Std. Error CI (95%) Statistic P-value

Assessment, Group type
 Intercept 0.740 0.556 [−0.351, 1.831] 1.331 0.184
 Assessment −0.034 0.082 [−0.195, 0.126] −0.422 0.673
 pMCI group 3.918 0.659 [2.625. 5.212] 5.950 <0.001
 Assessment * pMCI group 0.372 0.095 [0.186, 0.558] 3.930 <0.001
Assessment, Group type, Sex
 Intercept 0.815 0.969 [−1.088, 2.719] 0.841 0.401
 Assessment time −0.037 0.125 [−0.282, 0.208] −0.299 0.765
 pMCI group 4.053 1.126 [1.842, 6.265] 3.599 <0.001
 Males −0.108 1.190 [−2.445, 2.229] −0.091 0.928
 Assessment * pMCI group 0.607 0.143 [0.327, 0.888] 4.254 <0.001
 Assessment * Males −0.000 0.158 [−0.310, 0.310] −0.001 1.000
 pMCI diagnosis * Males −0.212 1.398 [−2.957, 2.533] −0.152 0.879
 Assessment * pMCI group * Males −0.397 0.182 [−0.754, −0.040] −2.186 0.029
Assessment, Group type, APOEε4
 Intercept 0.585 0.576 [−0.546, 1.716] 1.015 0.310
 Assessment −0.010 0.093 [−0.193, 0.173] −0.109 0.913
 pMCI group 3.612 0.717 [2.203, 5.020] 5.036 <0.001
 APOEε4 carrier 0.672 0.651 [−0.607, 1.950] 1.032 0.303
 Assessment * pMCI group 0.136 0.119 [−0.098, 0.371] 1.142 0.254
 Assessment * APOEε4 carrier −0.092 0.182 [−0.449, 0.264] −0.509 0.611
 Assessment * pMCI group * APOEε4 carrier 0.435 0.205 [0.033, 0.837] 2.123 0.034