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MC-EXOs and TGF-β have an additive effect on collagen synthesis in HLFs. Secreted collagen measurements in the supernatants of HLF s and HLFs incubated with MC-EXO (40 μg) or TGF-β (10 ng/ml) with and without the TGF-βR1 inhibitor SB525334 (10 μM) for 72 h. All assays were performed in triplicate and normalized to total protein (μg). *P < 0.05, **P < 0.01, n = 5 samples/group.
