Table 1.

Sampling information table.

Group	Sample number	Sex	Age	Site	Altitude	Sample source
	HH1	Female	21				HH2	Female	21	HH3	Female	21	HH4	Female	20	HH5	Female	21	Lhasa City, Tibet	3650	Fecal	HH6	Male	21	HH7	Male	22				HH8	Male	22				HH9	Male	21
High altitude Human (HH)	HH10	Male	21
	HH11	Female	46				HH12	Female	41				HH13	Female	38	HH14	Female	46	HH15	Female	45	Linzhou County, Lhasa City, Tibet	3900	Fecal	HH16	Male	53	HH17	Male	37				HH18	Male	28	HH19	Male	34	HH20	Male	44
High altitude Dog (HD)	HD1-20	—	—	Lhasa stray dog shelter	3650	Fecal
High altitude Rhesus macaques (HM)	HM1-19	—	Adult	Gongbujiangda County, Linzhi City	3400	Fecal
	LH1	Female	25				LH2	Female	24	LH3	Female	25	LH4	Female	22	LH5	Female	22	LH6	Male	25	LH7	Male	24	LH8	Male	24	LH9	Male	26
Low altitude Human (LH)	LH10	Male	29	Ya’an, Sichuan	560	Fecal
	LH11	Female	44
	LH12	Female	47				LH13	Female	46	LH14	Female	45	LH15	Female	46	LH16	Male	46	LH17	Male	47	LH18	Male	48	LH19	Male	45	LH20	Male	47
Low altitude Dog (LD)	LD1-20	—	—	Ya’an stray dog shelter	590	Fecal
Low altitude Rhesus macaques (LM)	LM1-10	—	Adult	Jiangjin County, Chongqing City	895	Fecal
	LM11-20	—	Adult	Fengjie County, Chongqing City	220	PRJNA535368	LM21-35	—	Adult	Longhushan, Guangxi	220	PRJNA535368
Low altitude Coyote (LW)	LM1-18	—	—	Dround Edmonton, Alberta, Canada	-	PRJNA528764
						PRJNA528765