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. 2023 Feb 23;14:1034170. doi: 10.3389/fphys.2023.1034170

FIGURE 2.

FIGURE 2

Renin–angiotensin system in the pathophysiology of coronary heart disease [overactivated renin–angiotensin system causes the activation of various harmful signaling pathways of inflammation and/or oxidative stress, or the harmful lipid molecules cause endothelial dysfunction, which exacerbates the process of coronary heart disease].