Table 2.
Group/Subgroup | Khorana Cutoff | Odds Ratio | Confidence Interval | p Value | Sensitivity | Specificity | PPV | NPV | AUC | Likelihood Ratio (+) |
---|---|---|---|---|---|---|---|---|---|---|
All | K ≥ 2 | 1.17 | 0.40–3.39 | 0.77 | 0.72 | 0.31 | 0.068 | 0.94 | 0.51 | 1.05 |
All | K ≥ 3 | 1.69 | 0.61–4.69 | 0.35 | 0.33 | 0.77 | 0.092 | 0.94 | 0.55 | 1.46 |
ACT | K ≥ 2 | 1.05 | 0.31–3.53 | 0.94 | 0.69 | 0.32 | 0.056 | 0.95 | 0.51 | 1.02 |
ACT | K ≥ 3 | 2.69 | 0.84–8.65 | 0.09 | 0.38 | 0.81 | 0.11 | 0.96 | 0.60 | 2.04 |
NA/DCT | K ≥ 2 | 1.38 | 0.14–14.07 | 0.78 | 0.80 | 0.26 | 0.13 | 0.90 | 0.53 | 1.08 |
NA/DCT | K ≥ 3 | 0.27 | 0.027–2.61 | 0.25 | 0.20 | 0.51 | 0.056 | 0.82 | 0.64 | 0.41 |
ACT = adjuvant chemotherapy, K = Khorana score, NA/DCT = neoadjuvant/definitive chemotherapy, NPV = negative predictive value, PPV = positive predictive value,