Table 1.
Demographics, cognitive performance in study cohorts.
| Total | Cognitively normal | MCI | Dementia | p1−3 | ||
|---|---|---|---|---|---|---|
| n = 1,302 | n1=287 (22.04%) | n2=646 (49.62%) | n3=369 (28.34%) | |||
| Years | ||||||
| Age | 75.74 [71.7–80.7] | 76.62 ± 5.62 | 75.25 ± 7.16 | 75.93 ± 7.37 | 0.0933785 | |
| Education | 15.58 [13.0–18.0] | 16.13 ± 2.91 | 15.76 ± 2.99 | 14.85 ± 3.21* | 9.08991e-08 | |
| Sex | ||||||
| Women | 522 (40.09%) | 134 (46.69%) | 215 (33.28%) | 173 (46.88%) | 4.19707e-06 | |
| Men | 780 (59.91%) | 153 (53.31%) | 431 (66.72%) | 196 (53.12%) | ||
| Race | ||||||
| Whites | 1,210 (92.93%) | 261 (90.94%) | 603 (93.34%) | 346 (93.77%) | 0.198438 | |
| Blacks | 60 (4.61%) | 21 (7.32%) | 22 (3.41%) | 17 (4.61%) | ||
| Asians | 30 (2.3%) | 5 (1.74%) | 19 (2.94%) | 6 (1.63%) | ||
|
Test
result | ||||||
| ADAS-cog | 19.87 [11.7–26.3] | 8.73 ± 4.14 | 18.82 ± 6.6 | 30.37 ± 8.97 | 2.2404e-165 | |
| MMSE | 26.18 [24.0–29.0] | 29.06 ± 1.09 | 26.91 ± 2.2 | 22.66 ± 3.03 | 2.1560e-155 | |
| RAVLT | 30.44 [23.0–37.0] | 43.2 ± 9.76 | 29.79 ± 8.86 | 21.67 ± 7.77 | 3.7071e-120 | |
| DSST | 36.24 [27.0–45.0] | 46.77 ± 11.06 | 37.37 ± 11.1 | 26.05 ± 12.41 | 2.72808e-83 | |
| TMT | 138.13 [75.0–187.0] | 85.03 ± 43.18 | 128.48 ± 72.56 | 200.96 ± 88.57 | 2.20487e-73 |
p−value is marked in bold if difference among groups is statistically significant (p < 0.05).
Statistical data are reported as IQR, Mean±SD, or absolute number of cases and their percentage in studied cohort.
If the distribution of metrics differs significantly (p < 0.05) for an index compared to other ones, its Mean ± SD is marked with an asterisk.