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. 2023 Feb 17;25(4):154. doi: 10.3892/etm.2023.11853

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Copyright: © Yang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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KIF18A interacts with PPP1CA in glioblastoma cells. (A) Biological General Repository for Interaction Datasets and (B) GeneMANIA databases were utilized to analyse the interaction between KIF18A and PPP1CA. (C) Expression level of PPP1CA, (D) associated survival probability and (E) correlation with KIF18A were analysed utilizing the Chinese Glioma Genome Atlas database. The expression level of PPP1CA was measured via (F) reverse transcription-quantitative PCR and (G) western blot analysis. (H) IP was utilized to investigate the targeted binding relationship between KIF18A and PPP1CA. ^***P<0.001. KIF18A, kinesin family member 18A; PPP1CA protein phosphatase 1 catalytic subunit α; WHO, World Health Organization; IP, immunoprecipitation.