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. 2023 Feb 23;10:1083455. doi: 10.3389/fnut.2023.1083455

Table 1.

Univariable causal effects of fatty acids on atopic dermatitis.

Exposure Outcome No. SNPs MR method P OR Lower 95% CI limit Upper 95% CI limit
Omega-6 fatty acids atopic dermatitis 51 IVW 0.27 0.96 0.90 1.03
Weighted median 0.82 1.01 0.92 1.11
Weighted mode 0.66 1.03 0.91 1.16
MR Egger 0.80 0.98 0.85 1.13
Omega-3 fatty acids 48 IVW 0.01 0.92 0.87 0.98
Weighted median <0.001 0.90 0.85 0.95
Weighted mode 0.003 0.91 0.86 0.97
MR Egger 0.08 0.92 0.85 1.01
Polyunsaturated fatty acids 53 IVW 0.08 0.94 0.87 1.01
Weighted median 0.69 0.98 0.89 1.08
Weighted mode 0.67 1.03 0.91 1.16
MR Egger 0.89 0.99 0.86 1.14
Saturated fatty acids 47 IVW 0.25 0.95 0.87 1.04
Weighted median 0.51 1.03 0.94 1.14
Weighted mode 0.56 1.03 0.93 1.15
MR Egger 0.45 1.06 0.91 1.23
Monounsaturated fatty acids 56 IVW 0.37 0.96 0.88 1.05
Weighted median 0.27 0.95 0.87 1.04
Weighted mode 0.84 0.99 0.90 1.09
MR Egger 0.87 1.01 0.88 1.17