Figure S8.

ML385 abrogates the function of IR-61 to enhance the phagocytosis of human macrophages. Human macrophages were treated with ML385 2 h before IR-61 incubation. After 24 h, the cells were incubated with pHrodo-labelled E. coli for another 1 h. Uptake was measured by fluorescent microscopy (ML385 vs ML385+IR-61 p = 0.7328; n = 3 plates of human macrophages per group and random observation of 3 visual fields per plate; bars represent 100 μm). Results are presented as the mean ± SD (two-sided Student’s t-test).