Fig. 3.

Inter-fractional changes of gross target volume for all the brain lesions. (A) The ΔV, DSC and HD of GTV at Fx1, Fx2, Fx3, Fx4 and Fx5 for all the brain lesions (n = 88). (B) Axial slices of a case at planning (Fx0), fraction 1, 2, 3, 4 and 5 (Fx1, Fx2, Fx3, Fx4 and Fx5), illustrating patient-specific serial gross tumor volume changes. The planned GTV (baseline, Fx0) was contoured in white-line and the GTVs from daily MR scans (Fx1-5) were in red-line; the Fx0 delineation was also interpolated post registration to daily MRI for comparison migration. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)