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. 2022 Nov 14;36(3):385–403. doi: 10.5713/ab.22.0325

Figure 1.

Figure 1

The balance and impacts of reactive oxygen species (ROS) on sperm fertilizing ability. ROS can be released physiologically and on a minimal level they play a role in sperm maturation, capacitation, and acrosome reaction. Paradoxically, high levels of ROS damage the sperm membrane lipids and the nuclear DNA and lead to subfertility and infertility. The balance can be adjusted by administration of several kinds of antioxidants to treat the subfertility and infertility cases.