Figure 1.
CTHRC1 expression levels in different types of human cancer. (A) The transcription levels of human CTHRC1 in different tumor types in the TCGA database were assessed using TIMER. (B) CTHRC1 transcriptional levels in adjacent and tumor tissues in patients with HNSCC from the TCGA database. (C) Expression level of CTHRC1 in different cancer datasets compared with normal tissues in the ONCOMINE database, the number indicated the number of data sets included by The National Center for Biotechnology Information that matched the conditions. (D) Scatter plot of CTHRC1 expression (using H-score) in HNSCC tissues compared with normal tissues. (E) Representative immunohistochemistry of CTHRC1 in clinical specimens. *P<0.05, **P<0.01, ***P<0.001. TCGA, The Cancer Genome Atlas; ACC, adrenocortical carcinoma; BLCA, bladder urothelial carcinoma; BRCA, breast invasive carcinoma; CESC, cervical squamous cell carcinoma and endocervical adenocarcinoma; CHOL, cholangio carcinoma; CNS, central nervous system; COAD, colon adenocarcinoma; DLBC, lymphoid neoplasm diffuse large B-cell lymphoma; ESCA, esophageal carcinoma; GBM, glioblastoma multiforme; HNSC, head and neck squamous cell carcinoma; HPV, human papillomavirus; neg, negative; pos, positive; KICH, kidney chromophobe; KIRC, kidney renal clear cell carcinoma; KIRP, kidney renal papillary cell carcinoma; LGG, (brain) lower grade glioma; LIHC, liver hepatocellular carcinoma; LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma; MESO, mesothelioma; OV, ovarian serous cystadenocarcinoma; PAAD, pancreatic adenocarcinoma; PCPG, pheochromocytoma and paraganglioma; PRAD, prostate adenocarcinoma; READ, rectum adenocarcinoma; SARC, sarcoma; SKCM, skin cutaneous melanoma; STAD, stomach adenocarcinoma; TGCT, testicular germ cell tumor; THCA, thyroid carcinoma; THYM, thymoma, UCEC, uterine corpus endometrial carcinoma; UCS, uterine carcinosarcoma; UVM, uveal melanoma; CTHRC1, collagen triple helix repeat containing 1; TPM, transcripts per million.
