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. 2023 Feb 23;11:1017660. doi: 10.3389/fcell.2023.1017660

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Copyright © 2023 Contreras and Harvey.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Muscle injury triggers a fast and strong downregulation LPA receptors in fibro-adipogenic progenitors. (A) Violin plots showing the gene expression level of LPAR family members and dynamics in response to injury. DPI, Days post-injury. (B) Heat map showing gene expression levels of Lpar, Enpp2, and Plpp genes in Hic1⁺ tdTomato expressing cells upon acute muscle damage (Scott et al., 2019). (C) Quantification of Lpar _(1–6) genes transcript abundance (FPKM) in Hic1⁺ tdTomato expressing cells and dynamics in response to injury.