Figure 1.

rs35888506 and rs2854320 are predicted to affect NF1 splicing

(A) and (B) show the predicted splicing events for rs35888506 and rs2854320 (locations denoted by the star symbols), respectively. For each panel, vertically aligned exons have identical chromosomal locations, although the positions of stop codons at the last exons and the end of the 3′ untranslated regions may vary. AE, alternative exon mapped to the canonical transcript; PTC-NMD, premature terminating codon-nonsense-mediated decay).