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. Author manuscript; available in PMC: 2023 Mar 9.
Published in final edited form as: ACS Appl Mater Interfaces. 2018 Nov 28;10(49):41892–41901. doi: 10.1021/acsami.8b08920

Figure 1.

Figure 1.

Genetic manipulation permits tunability of tissue-derived hydrogels. (A) Schematic of hydrogel preparation and example macroscopic image of hydrogel. (B) Optical density during gelation and (C) the time to half gelation of 4 mg/mL hydrogels (n = 5). (D–F) Representative SEM images of (D) WT, (E) 1:1, and (F) TSP-2 KO gel show similar structures. Scale bars = 5 μm. (G) Rheology reveals overall changes in maxima and suggests tunability of mechanical properties between WT, TSP-2 KO, and a 1:1 mixture (rheological traces are given as mean ± SEM). (H) Analysis of rheological data indicates significant changes between maximum storage moduli with genotype of matrix (n = 3). Results are given as mean + SEM, *p < 0.05, **p < 0.01, ***p < 0.005.