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. 2023 Mar 9;61(3):2201596. doi: 10.1183/13993003.01596-2022

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Forest plots for summary estimates (geometric mean (95% CI)) of dose-normalised peak plasma concentration (C_max) for a) isoniazid, b) rifampicin, c) pyrazinamide and d) ethambutol in children and adolescents with tuberculosis, by sampling schedules (steady-state and non-steady-state). C_max values were dose-normalised for isoniazid at 10 mg·kg⁻¹, rifampicin at 15 mg·kg⁻¹, pyrazinamide at 35 mg·kg⁻¹ and ethambutol at 20 mg·kg⁻¹. The number in round brackets after the author's name indicates the different sampling occasions within a study. I²: percentage of variation across studies that is due to heterogeneity; Q_M: omnibus test of all model coefficients.

Forest plots for summary estimates (geometric mean (95% CI)) of dose-normalised peak plasma concentration (C_max) for a) isoniazid, b) rifampicin, c) pyrazinamide and d) ethambutol in children and adolescents with tuberculosis, by sampling schedules (steady-state and non-steady-state). C_max values were dose-normalised for isoniazid at 10 mg·kg⁻¹, rifampicin at 15 mg·kg⁻¹, pyrazinamide at 35 mg·kg⁻¹ and ethambutol at 20 mg·kg⁻¹. The number in round brackets after the author's name indicates the different sampling occasions within a study. I²: percentage of variation across studies that is due to heterogeneity; Q_M: omnibus test of all model coefficients.