Table 3.
Diagnostic performance of nanopore sequencing assay, MGIT culture, and Xpert assay in PTB
PTB | Non-PTB | Sensitivity | Specificity | PPV | NPV | Coincidence | Kappa | |
---|---|---|---|---|---|---|---|---|
MGIT culture | 48.28 | 65.38 | 60.87 | 53.13 | 56.36 | 0.14 | ||
Positive | 14 | 9 | ||||||
Negative | 15 | 17 | ||||||
Xpert | 41.38 | 100 | 100 | 60.47 | 69.09 | 0.40 | ||
Positive | 12 | 0 | ||||||
Negative | 17 | 26 | ||||||
Nanopore sequencing assay | 75.86 | 80.77 | 81.48 | 75.00 | 78.18 | 0.56 | ||
Positive | 22 | 5 | ||||||
Negative | 7 | 21 |
PTB pulmonary tuberculosis, Non-PTB non-pulmonary tuberculosis, PPV positive predictive value, NPV negative predictive value