Table 2.

Variance analysis in the complete group of children with obesity (n = 63)

	1er Tercile ALT	2º Tercile ALT	3er Tercile ALT	F	p
ALT (U/L)	15.48 ± 0.36	19.26 ± 0.18	24.18 ± 0.72	209.83	< 0.001
Age (years)	8.69 ± 0.24	9.10 ± 0.19	8.97 ± 0.19	1.18	0.318
BMI (Kg/m2)	21.17 ± 1.19	22.88 ± 0.39	24,68 ± 0.47	4.91	0.025
SDS-BMI	2.46 ± 0.31	2.71 ± 0.17	3.50 ± 0.202	4.90	0.017
WC	71.95 ± 1.48	74.51 ± 1.37	78.40 ± 1.94	3.91	0.028
Glucose (mmol/L)	5.05 ± 0.08	4.98 ± 0.09	5.11 ± 0.06	0.72	0.495
Insulin (pmol/L)	43.06 ± 3.43	47.41 ± 3.65	59.44 ± 3.72	4.17	0.023
HOMA-IR	1.275 ± 0.11	1.491 ± 0.11	1.791 ± 0.12	5.07	0.011
Leptin (ng/mL)	16.61 ± 1.74	21.37 ± 2.17	26.35 ± 2.27	5.29	0.009
AST (U/L)	23.10 ± 0.90	23.82 ± 0.48	25.26 ± 0.96	1.99	0.150
BChE (U/L)	9514.8 ± 314.4	10,026.6 ± 145.8	10,294.2 ± 299.4	2.47	0.098
SBP (mm Hg)	98.71 ± 1.59	100.86 ± 1.12	100.38 ± 1.67	0.50	0.605
DBP (mm Hg)	60.43 ± 1.46	58.67 ± 0.90	59.81 ± 1.26	0.55	0.581
TC (mmol/L)	4.46 ± 0.12	4.44 ± 0.11	4.50 ± 0.17	0.06	0.943
TG (mmol/L)	0.78 ± 0.04	0.81 ± 0.04	0.92 ± 0.06	2.01	0.147
HDL-c (mmol/L)	1.37 ± 0.05	1.35 ± 0.03	1.36 ± 0.05	0.047	0.934
CRP (nmol/L)	18.96 ± 4.48	16.48 ± 2.47	25.10 ± 3.31	1.58	0.219
IL-6 (pg/mL)	1.36 ± 0.18	1.47 ± 0.08	1.52 ± 0.21	0.21	0.784
NLR	1.26 ± 0.14	1.05 ± 0.05	1.19 ± 0.07	1.37	0.266
PLR	97.27 ± 5.97	109.59 ± 6.39	103.27 ± 5.69	1.10	0.338
sICAM-1 (ng/mL)	278.51 ± 11.61	266.64 ± 8.33	267.40 ± 7.81	0.53	0.594

Results after treatment for nine months, stratified by ALT divided into terciles

ALT Alanine aminotransferase, BMI Body mass index, WC Waist circumference, HOMA-IR homeostasis model assessment for insulin resistance, AST Aspartate aminotransferase, BChE Butyryl cholinesterase, SBP Systolic blood pressure, DBP Diastolic blood pressure, TC Total cholesterol, TG Triglycerides, HDL-c HDL-cholesterol, CRP C-reactive protein, IL-6 Interleukin-6, NLR Neutrophil-to-lymphocyte ratio, PLR Platelet-to-lymphocyte ratio, sICAM-1 Soluble intercellular adhesion molecule-1. Results are expressed as the mean ± S.E.M