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. 2023 Mar 8;15:37. doi: 10.1186/s13098-023-00993-3

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Caffeine alleviated the Hyperlipidemia in the HFD-mice. (A) Caffeine high-dose treatment decreased the body weight and liver weight in obese mice. (B) Caffeine high-dose significantly improved Hyperlipidemia compared with the HFD group. c Caffeine high-dose intervention decreased random blood sugar in obese mice. NCD, HFD, caffeine low-dose and caffeine high-dose (n == 9/10 per group) groups. Data are presented as the mean± SEM. *p < 0.05; **p < 0.0l;***p < 0.001 (HFD group versus NCD group, caffeine low-dose group, caffeine high-dose group)