Table 1.
Histopathological diagnoses and methylation-based classifications of the 13 tumour samples with a calibrated score < 0.9
| Cases | Histopathological re-evaluation | Prediction: family | CS: family |
|---|---|---|---|
| 1 | HGG NOS | Glioblastoma, IDH-wildtype | 0.83808 |
| 2 | HGG NOS | Pilocytic astrocytoma | 0.55519 |
| 3 | HGG NOS | Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype | 0.82513 |
| 4 | HGG NOS | Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype | 0.65948 |
| 5 | HGG NOS | Glioblastoma, IDH-wildtype | 0.28580 |
| 6 | Diffuse midline glioma, H3-K27M altered | Diffuse midline glioma, H3K27-altered | 0.53717 |
| 7 | Diffuse hemispheric glioma, H3 G34-mutant | Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype | 0.50395 |
| 8 | IHG | Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype | 0.77386 |
| 9 | Highly malignant tumor NOS | Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype | 0.50582 |
| 10 | CPC | Choroid plexus tumours | 0.81520 |
| 11 | AT/RT | Atypical teratoid rhabdoid tumour | 0.70174 |
| 12 | Ewing tumor with CIC::DUX fusion | NA | NA |
| 13 | Unclassifiable | Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype | 0.71402 |
HGG NOS, High-grade glioma not otherwise specified; IHG, Infant-type hemispheric glioma; AT/RT, atypical teratoid rhabdoid tumour