Table 2.
Predictors of survival in the uni- and multivariable analysis
| Variables | Univariable analysis | Multivariable Cox regression analysis | ||
|---|---|---|---|---|
| p-value | n | p-value | n | |
| Hypochromic erythrocytes | 0.043 | 170 | ||
| White blood cell count | 0.298 | 170 | ||
| Ferritin | 0.353 | 160 | ||
| Iron | 0.702 | 160 | ||
| Hemoglobin | 0.290 | 170 | ||
| MCH | 0.301 | 170 | ||
| MCV | 0.143 | 170 | ||
| Categoriala | ||||
| MCV ≤ 80 fl | 0.920 | 163 | ||
| Hypochromic erythrocytes > 2% | 0.018 | 163 | 0.031 | 145 |
| Known prognostic predictors | ||||
| Sex | 0.322 | 163 | ||
| Type of SSc | 0.679 | 163 | ||
| DLCO ≤ 65% predicted | < 0.001 | 149 | 0.013 | 145 |
| ILD presence | 0.066 | 163 | ||
| Age ≥ 60 years, baseline | 0.040 | 160 | ||
| PVR ≥ 2 WU | 0.041 | 161 | ||
MCV mean corpuscular volume, SSc systemic sclerosis, DLCO diffusion capacity of the lung for carbon monoxide, ILD interstitial lung disease, PVR pulmonary vascular resistance
aUnivariable categorical analyses were performed with Kaplan-Meier analysis, and all other analyses were Cox regression analyses