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. 2023 Mar 9;25:38. doi: 10.1186/s13075-023-03020-y

Table 2.

Predictors of survival in the uni- and multivariable analysis

Variables Univariable analysis Multivariable Cox regression analysis
p-value n p-value n
Hypochromic erythrocytes 0.043 170
White blood cell count 0.298 170
Ferritin 0.353 160
Iron 0.702 160
Hemoglobin 0.290 170
MCH 0.301 170
MCV 0.143 170
Categoriala
 MCV ≤ 80 fl 0.920 163
 Hypochromic erythrocytes > 2% 0.018 163 0.031 145
Known prognostic predictors
 Sex 0.322 163
 Type of SSc 0.679 163
 DLCO ≤ 65% predicted < 0.001 149 0.013 145
 ILD presence 0.066 163
 Age ≥ 60 years, baseline 0.040 160
 PVR ≥ 2 WU 0.041 161

MCV mean corpuscular volume, SSc systemic sclerosis, DLCO diffusion capacity of the lung for carbon monoxide, ILD interstitial lung disease, PVR pulmonary vascular resistance

aUnivariable categorical analyses were performed with Kaplan-Meier analysis, and all other analyses were Cox regression analyses