Table 2.
Characteristics of liver/liver-kidney donors, according to HIV status.
| Characteristics | HIV D+ (N=24) | HIV D−a (N=21) | p-value |
|---|---|---|---|
| Age (years), median (IQR) | 36 (29, 44) | 39 (28, 44) | 0.63 |
| Male sex, no. (%) | 19 (79) | 14 (67) | 0.34 |
| Race, no. (%) | 0.42 | ||
| White | 10 (40) | 10 (48) | |
| Black | 12 (50) | 7 (33) | |
| Other | 2 (4) | 1 (5) | |
| Hispanic ethnicityb, no. (%) | 2 (8) | 4 (19) | 0.40 |
| BMI (kg/m2), median (IQR) | 24 (22, 26) | 26 (24, 33) | 0.14 |
| Hypertension, no. (%) | 6 (25) | 6 (29) | 0.79 |
| Diabetes, no. (%) | 2 (8) | 2 (10) | >0.99 |
| Cancer, no. (%) | 1 (4) | 0 (0) | >0.99 |
| Blood type, no. (%) | 0.80 | ||
| O | 15 (63) | 13 (62) | |
| A | 8 (33) | 6 (29) | |
| B | 1 (4) | 2 (10) | |
| Brain death donors, no. (%) | 24 (100) | 20 (95) | 0.47 |
| Cause of death, no. (%) | >0.99 | ||
| Anoxia | 12 (50) | 10 (48) | |
| Cerebrovascular/Stroke | 5 (21) | 5 (24) | |
| Head Trauma | 6 (25) | 5 (24) | |
| Other |
1 (4) | 1 (5) | |
| HIV and co-infection characteristics |
|||
| HIV acquisition risk | NA | - | |
| Men who have sex with men, no. (%) | 9 (38) | ||
| Heterosexual sex | 7 (29) | ||
| Injection drug use | 4 (17) | ||
| Other/unknown | 7 (29) | ||
| CD4 T cell count, median (IQR) | 329 (121, 609) | NA | - |
| HIV Ab positive, no. (%) | 24 (100) | 7 (33) | <0.001 |
| HIV qualitative NAT positive, no. (%)c | 17 (71) | 2 (10)d | <0.001 |
| HBV qualitative NAT positive, no. (%)d | 0 (0) | 0 (0) | - |
| HCV qualitative NAT positive, no. (%) | 1 (4) | 4 (19) | 0.17 |
| CMV IgG positive, no (%) | 21 (88) | 13 (62) | 0.08 |
| HHV8 Ab positive, no. (%)e | 6 (26) | 0 (0) | 0.15 |
| New HIV diagnosis, no. (%) | 6 (25) | NA | - |
| Of those with known HIV, on ART, no. (%)f | 16 (89) | ||
| Of those on ART, HIV RNA<400 (copies/mL), no. (%) | 13 (81) | ||
| Of those off ART, HIV RNA (copies/mL), median (IQR) | 46,524 (15,488, 184,182) | ||
| Injection drug use, no. (%) | 3 (13) | 5 (24) | 0.44 |
a
Includes 10 donors with false positive HIV screening tests that were negative on confirmatory testing
b
Two recipients identified as race other and ethnicity Hispanic/Latino
c
Negative in 6 donors on ART who had positive HIV Ab
d
Confirmatory quantitative HIV NAT was undetectable
e
Missing in 1 D+ and 12 D−
f
1 D+ with known HIV but unknown ART status
Ab, antibody; ART, antiretroviral therapy; BMI, body mass index; HCV, hepatitis C virus; HIV, human immunodeficiency virus; HHV8, Human Herpesvirus-8 IQR, interquartile range; IV, NA, not applicable; NAT, nucleic acid testing, ND, not done; RNA, ribonucleic acid.