Table 4.
Post-transplant time-to-event and recurrent outcomes for liver and simultaneous liver-kidney recipients by donor HIV status, after weighting.
| Outcomes | Estimate (95% CI) | p-value |
|---|---|---|
| Time-to-event |
||
| Mortality, wHR | 6.55 (1.11-38.60) | 0.04 |
| Cancer, wHR |
7.34 (1.48-36.39) | 0.02 |
| Recurrent events |
||
| Rejection episodes, wIRR | 0.91 (0.19-4.23) | 0.90 |
| IR HIV D+/R+ (per 100 person-years) | 15.3 (6.3-37.2) | |
| IR HIV D−/R+ (per 100 person years) | 16.8 (5.0-56.2) | |
| SAEs, wIRR | 1.60 (0.83-3.06) | 0.16 |
| IR HIV D+/R+ (per 100 person-years) | 188.6 (118.1-301.1) | |
| IR HIV D−/R+ (per 100 person years) | 118.2 (75.0-186.3) | |
| Infectious hospitalization, wIRR | 4.25 (1.43-12.62) | 0.009 |
| IR HIV D+/R+ (per 100 person-years) | 73.8 (39.0-139.9) | |
| IR HIV D−/R+ (per 100 person years) | 17.4 (7.3-41.1) | |
| Opportunistic infection, wIRR | 5.37 (1.32-21.83) | 0.02 |
| IR HIV D+/R+ (per 100 person-years) | 20.8 (8.8-48.8) | |
| IR HIV D−/R+ (per 100 person years) | 3.9 (1.3-11.8) | |
| HIV breakthrough, wIRR | 0.90 (0.12-6.58) | 0.92 |
| IR HIV D+/R+ (per 100 person-years) | 4.2 (1.1-16.3) | |
| IR HIV D−/R+ (per 100 person years) | 4.7 (1.1-19.5) |
CI, confidence interval; IR, incidence rate; SAE, serious adverse event; wHR, weighted hazard ratio; wIRR, weighted incidence rate ratio.