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. Author manuscript; available in PMC: 2023 Mar 9.
Published in final edited form as: Addict Neurosci. 2023 Jan 10;5:100062. doi: 10.1016/j.addicn.2023.100062

Table 1.

Two-Way ANOVA Outputs for 5d Abstinence NAc core Cytokine, Chemokine, and Growth Factor Expression.

Target Reinforcer p-value Microinjection p-value Reinf.*Micro. p-value

Eotaxin F(1,13) = 12.29 p = 0.0034 F(1,13) = 1.27 ns F(1,13) = 10.01 p = 0.008
CX3CL1 F(1,13) = 47.22 p < 0.0001 F(1,13) = 0.0002 ns F(1,13) = 0.013 ns
GM-CSF F(1,13) = 1.730 ns F(1,13) = 6.71 p = 0.0224 F(1,13) = 3.663 ns
IFNγ F(1,13) = 16.62 p = 0.0013 F(1,13) = 0.873 ns F(1,13) = 9.079 p = 0.01
IL-4 F(1,13) = 42.42 p < 0.0001 F(1,13) = 0.003 ns F(1,13) = 0.011 ns
IL-5 F(1,13) = 34.94 p < 0.0001 F(1,13) = 3.636 ns F(1,13) = 0.907 ns
IL-18 F(1,13) = 75.45 p < 0.0001 F(1,13) = 4.386 ns F(1,13) = 0.727 ns
CXCL2 F(1,13) = 19.91 p = 0.0006 F(1,13) = 5.885 p = 0.0306 F(1,13) = 6.544 p = 0.024
CCL5 F(1,13) = 30.22 p = 0.0001 F(1,13) = 19.84 p = 0.0006 F(1,13) = 0.089 ns
VEGF F(1,13) = 6.43 p = 0.0248 F(1,13) = 4.57 ns F(1,13) = 15.35 p = 0.002