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. 2023 Mar 5;16:143–155. doi: 10.2147/OTT.S397593

Box 2.

Natural Antioxidants of Prophetic Medicine are Promising for Preventing and Treating the Warburg Effect

*This occurs due to the so many natural antioxidant ingredients that may antagonize the Warburg effect (lactate-induced increased oxidative stress).
*Natural and nutritional antioxidant ingredients may cause antioxidant–oxidant antagonism.
*Natural and nutritional antioxidant ingredients may cause antioxidant–lactate (pro-oxidant) antagonism.
*******Such promising natural antioxidants include:
  1. Ajwa date fruit (Phoenix dactylifera) rich in polyphenols, flavonoids, and antioxidant minerals.

  2. Al-hijamah via direct percutaneous excretion of oxidants (as malondialdehyde) and lactate.

  3. Natural honey rich in polyphenols and flavonoids.

  4. Nigella sativa rich in thymoquinone, nigellone, carvacrol, carvone, α-pinene, and others.

  5. Costus (Saussurea lappa) rich in costunolide and dehydrocostus lactone and santamarin.

  6. Senna (Cassia angustifolia) rich in sennosides, emodin, cassine, alaternin, and norrubrofusarin.

  7. Fennel (Foeniculum vulgare Mill) rich in anethol, limonene, fenchone, and flavonoids.

  8. Olive oil rich in oleic acid, hydroxytyrosol, oleuropein, homovanillic acid, and alcohol.

  9. Barley rich in glutathione S-transferases antioxidant enzymes, phenolics,and β-glucan fibres.

  10. Zamzam water (alkaline pH) rich in antioxidant minerals: selenium, strontium, Zn, Mg, and Mn.

  11. Apple cider vinegar rich in gallic acid, chlorogenic acid, tyrosol, caftaric acid, and resveratrol.

  12. Desert truffles rich in phenolic antioxidants (caffeic acid), amino acids, and minerals eg Mg.

  13. Camel milk rich in aliphatic alcohols and aldehydes and sulphur-containing compounds.

  14. Camel urine rich in canavanine, d-glucuronic acid, and antioxidant minerals.

  15. Henna (Lawsonia inermis) rich in Lawson, coumarin, quinones, and flavonoids.