Fig 7. Effect size of selected SNPs on ETDRS grid.
The figure shows the effect size of the SNPs (shown by a blue-red gradient) with differential effect on the concentric fields of the retina, on the nine different segments of the ETDRS grid across the three PRC layers listed from top to bottom: ONL, IS and OS. Six loci are visualised: RREB1 (rs75757892), TMEM106B (rs13237518), RDH5 (rs3138142), MERTK (rs869016), CDHR1 (rs55798570), and RAX2 (rs76076446). Effect sizes are scaled for each genetic locus individually.