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. 2023 Jan 30;7(3):424–439. doi: 10.1038/s41559-022-01980-z

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 9 — Earlier (a, b) and later (c, d) stage of Prophase I cells of different individuals are shown. DAPI staining is shown in grey. a, b, single nuclei are circled by dotted lines. The arrow indicates the cluster of signals of ChrIR. The additional FISH signals of ChrIR were distantly located in 3 out of 10 individuals (e. g. b, d), whereas only one cluster was found in the others (e. g. a, c). Such a variation did not happen with ChrIL and ChrX. These pictures were obtained in the Z-stack projection. The scale bar is 5 µm.