Table 1.
Human Endometrial Stem Cells.
| Surface markers | Cell type | Location | Function | Reference |
|---|---|---|---|---|
| TERT | Epithelial | Glandular | Correlated with epithelial proliferation | 55 |
| CD326 (EPCAM) | Epithelial | Basalis and functionalis | Endometrial EpCAM(+) epithelial cells own great proliferation abilities | 56 |
| SOX9 | Epithelial | Basalis (46.2–52.3%) functionalis (8–12.1%) | Epithelial repair and glandular regeneration | 47 |
| SSEA1 | Epithelial | Basalis | Epithelial repair and glandular regeneration | 47 |
| CTNNB1 (β-catenin) | Epithelial | Basalis | Could have stem cell properties | 47 |
| Notch | Epithelial | Basalis and functionalis | Maintain cells in an undifferentiated state57 | 57 |
| CHD2 (N-cadherin) | Epithelial | Basalis | Glandular regeneration and self-renew | 49 |
| ALDH1AI | Epithelial | Deep glands of basalis | Endometrium regeneration, involved in the pathology of endometriosis | 52 |
| LRG5 | Epithelial | Luminal epithelium and stratum basalis | Correlate with epithelial proliferation | 50 |
| MSCA-1 (TNAP) | Stromal | Pericyte | High levels in the luminal space of glandular epithelia | 41 |
| W5C5 (SUSD2) | Stromal | Perivascular, basalis and functionalis | Reconstituting endometrial stromal tissues | 39 |
| CD146 PDGF-Rb (CD140b) | Stromal | Perivascular location in the basalis (mainly) | Colony-forming ability and multipotency | 38 |
| NTPDase2 | Stromal | Basalis | NTPDase2 was expressed by the SUSD2+ endometrial mesenchymal stem cells | 54 |
| c-KIT/CD117 | Epithelial/stromal | Mainly in the stroma of the basalis | Persistent from the fetal to the postmenopausal period | 37 |
| Musashi-1 | Epithelial/stromal | Basalis and functionalis | Progenitor cells in proliferating endometrium | 45 |