TABLE 4.

The compounds from natural products that inhibit PBP2a.

Name	Source	Mechanisms	Ref
Morin	Flavonol	Reducing the production of PBP2a	Mun et al. (2015)
Ursolic/Oleanolic acids	leaves of shea butter trees	Separating PBP2a from the cleavage site of the spacer	Catteau et al. (2017)
EGCG	Tea Camellia sinensis (L.) Kuntze leaves	Binding of peptidoglycans, reducing the production of PBP2a or its gene expression	Hu et al., 2001, Shiota et al., 1999
Corilagin/Tellimagrandin I		Inhibiting the activity of PBP2a	Shiota et al. (2004)
Baicalein		Inhibition of PBP2a or damage of peptidoglycans	Liu et al. (2000)
2,3,3-trimethyl-Octane and benzoic	Toxicodendron vernicifluum	Metabolizing PBP2a	Saravanakumar et al. (2019)