Table 3.
Permeability ratios for small intestinal permeability (0–2 h-L/R*103) distal small and proximal colonic permeability (2–5 h-S/E*103) and colonic permeability (5–24 h-S/E*103) in healthy controls, IgAN and non-IgAN GN patients
| 0–2 h-L/R*103 ratio | 2–5 h-S/E*103 ratio | 5–24 h-S/E*103 ratio | |
|---|---|---|---|
| Healthy controls (n = 19) | 21.66 ± 11.92 | 24.45 ± 14.63 | 21.56 ± 10.03 |
|
IgAN (n = 35) CKD 1–2 (n = 16) CKD 3–4 (n = 19) |
29.74 ± 15.51 30.17 ± 15.43 29.38 ± 15.99 |
24.87 ± 12.60 25.32 ± 10.91 24.49 ± 14.15 |
17.59 ± 6.97 18.68 ± 6.71 16.68 ± 7.24 |
|
Non-IgAN GNs (n = 18) CKD 1–2 (n = 13) CKD 3–4 (n = 5) |
36.77 ± 27.77# 27.04 ± 8.51 62.07 ± 44.19 |
29.53 ± 15.49 33.51 ± 15.76 19.16 ± 9.44 |
20.96 ± 14.36 23.52 ± 15.74 14.30 ± 7.53 |
Bold values indicate statistically significant differences at the 5% significance level. Exact p-values of the comparisons can be found in Fig. 1
L/R ratio ratio between lactulose and l-rhamnose, S/E ratio ratio between sucralose and erythritol, CKD chronic kidney disease, IgAN IgA Nephropathy. Values are presented as means and standard deviations
#p < 0.05 as compared to healthy controls